Date of Award
Bachelor of Science
Professor Harry Blaise
Dr. Joseph McIsaac MD, MS
This project sought to design and produce a device for the on-site manufacture of sterile water to be subsequently used to produce IV fluid in disaster zone. In order to accomplish this, the water produced must be pure, sterile, non-pyrogenic, and satisfy the United States Pharmacopeia (USP) standard for water for injection (WFI). Ideally, the device should be low powered, low cost, robust yet portable and deliver at least 10 liters per hour. Our design incorporated the purification methods of carbon filtration, reverse osmosis and Ultra-violet treatment. However, due to power and cost constraints our device was neither able to produce 10 liters per hour nor produce fluid sterile enough to satisfy USP 24 standards. Further improvements should include a more powerful pump for double pass reverse osmosis, more robust frame structure, portable power source and improved equipment sterilization techniques
Richardson, Chislon M. and Hebert, Jeff, "Device for on-site Production of Sterile Water for Injection in a Disaster Zone". Senior Theses, Trinity College, Hartford, CT 2013.
Trinity College Digital Repository, https://digitalrepository.trincoll.edu/theses/308